Treatment failure gout: failure to treat?
نویسندگان
چکیده
منابع مشابه
Treatment failure gout.
Treatment options for gout are well established and reasonably effective. They include anti-inflammatory agents such as non-steroidal anti-inflammatory drugs (NSAIDS), glucocorticoids and colchicine and urate-lowering therapies such as allopurinol and probenecid. However, despite the availability of effective urate-lowering therapy, there remains a subset of patients with gout who, despite aggr...
متن کاملFamilial gout and renal failure.
Clinical gout and renal failure was seen in a 9-year-old girl. The family tree showed that 9 out of 11 young females in three generations suffered from hyperuricaemia and normal (n = 1), or impaired (n = 8), renal function. One set of twins occurred in each generation and there is only one living male subject. In members with renal failure there was no improvement in renal function after treatm...
متن کاملFailure to Treat Torsades de Pointes
A healthy 22 year old male with no history of cardiac disease was admitted with severe community acquired pneumonia that was initially treated with moxifloxacin and azithromycin. At admission, he was found to be hypokalemic and hypomagnesemic. Two days after admission, he experienced several episodes of Torsades de Pointes (TdP). He was initially treated with isoproterenol. A temporary transven...
متن کاملUsing carvedilol to treat heart failure.
Despite current treatments, including use of angiotensin-converting enzyme (ACE) inhibitors, digoxin, and diuretics, morbidity and mortality remain alarmingly high. An estimated 50% of patients with severe signs and symptoms of heart failure will die within 1 year and 70% within 3 years. Additional pharmacological therapies to mitigate this disorder, such as β-blockers, continue to be investiga...
متن کاملGout, allopurinol use, and heart failure outcomes.
BACKGROUND Hyperuricemia is associated with reduced survival among patients with heart failure (HF), but the effect of gout on HF outcomes is unknown. A recent randomized trial suggested that allopurinol may reduce adverse outcomes among patients with hyperuricemia and HF. Our objective was to determine whether gout and allopurinol use are associated with HF outcomes. METHODS Time-matched, ne...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2010
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/keq143